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The Paradox Solution may help manage Refractory Pain from Fibromyalgia; however, the more co-morbidity, including narcotic dependency, the more difficulty in arriving at long term resolution of abnormal pain. A multidisciplinary approach is recommended in cases such as this, with consideration of close rheumatology, hematology (for IvIg) and orthopedic medical support, as well as physical therapy, nutritional supplements, massage, chiropracty, and other complementary medicine. Weaning off narcotics is very difficult and the patient should be prepared to face severe fatigue, diarrhea, intestinal cramps, depression, irritability, withdrawal related bone pain, mood changes, etc.
When patients appreciate relief of pain, they should be advised to resume normal activities slowly to avoid injury to joints and structures weakened by pain related disuse.